Zaijun Zhang Selected Research

DT-010

9/2017	A Novel Danshensu-Tetramethylpyrazine Conjugate DT-010 Provides Cardioprotection through the PGC-1α/Nrf2/HO-1 Pathway.
12/2016	Potent Protection Against MPP+-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine.

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Zaijun Zhang Research Topics

Disease

22	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 04/2015
18	Parkinson Disease (Parkinson's Disease) 04/2024 - 08/2012
15	Ischemic Stroke 01/2023 - 10/2008
11	Stroke (Strokes) 03/2024 - 10/2008
10	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 01/2012
9	Neoplasms (Cancer) 11/2017 - 06/2006
8	Inflammation (Inflammations) 08/2023 - 06/2015
6	Mitochondrial Diseases (Mitochondrial Disease) 04/2023 - 01/2017
5	Neuroinflammatory Diseases 04/2023 - 01/2017
5	Cognitive Dysfunction 01/2021 - 01/2016
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 09/2013
3	Fibrosis (Cirrhosis) 03/2024 - 01/2021
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2024 - 01/2019
3	Hypoxia (Hypoxemia) 01/2022 - 01/2017
3	Amyloid Plaque 01/2020 - 04/2015
3	Cerebral Infarction 01/2018 - 10/2015
2	Dementia (Dementias) 04/2024 - 01/2020
2	Brain Diseases (Brain Disorder) 03/2024 - 01/2018
2	Memory Disorders (Memory Loss) 04/2023 - 01/2020
2	Acute Lung Injury 12/2022 - 01/2019
2	Lung Neoplasms (Lung Cancer) 04/2022 - 01/2012
2	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2021 - 01/2019
2	Colitis 01/2020 - 01/2016
2	Pathologic Processes 01/2020 - 11/2017
2	Intracranial Vasospasm 01/2019 - 01/2019
2	Neuroblastoma 01/2018 - 10/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 09/2017 - 08/2015
2	Myocardial Infarction 09/2017 - 06/2015
2	Leukemia 05/2017 - 12/2015
2	Infarction (Infarctions) 01/2017 - 11/2016
2	Body Weight (Weight, Body) 01/2014 - 10/2010
2	Leukemia L1210 01/2012 - 06/2006
1	Starvation 11/2023
1	Non-alcoholic Fatty Liver Disease 08/2023
1	Fatty Liver 08/2023
1	Sleep Deprivation 06/2023
1	Sepsis (Septicemia) 12/2022
1	Lung Injury 12/2022
1	Septic Shock (Toxic Shock Syndrome) 12/2022

Drug/Important Bio-Agent (IBA)

19	Neuroprotective AgentsIBA 01/2023 - 10/2008
14	tetramethylpyrazineIBA 03/2024 - 01/2014
13	tetramethylpyrazine nitroneIBA 03/2024 - 01/2014
11	Proteins (Proteins, Gene)FDA Link 08/2023 - 02/2015
9	Free RadicalsIBA 01/2023 - 10/2008
8	Therapeutic UsesIBA 01/2023 - 01/2014
7	Memantine (Namenda)FDA Link 04/2024 - 01/2017
7	Thymidine Monophosphate (TMP)IBA 03/2024 - 10/2008
6	NitratesIBA 04/2024 - 01/2017
6	Amyloid (Amyloid Fibrils)IBA 02/2022 - 01/2018
5	N-Methylaspartate (NMDA)IBA 12/2022 - 01/2018
5	andrographolideIBA 01/2020 - 07/2009
4	SynucleinsIBA 04/2024 - 04/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024 - 06/2015
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 01/2018
4	Ephrin-A5 (AL-1)IBA 01/2020 - 07/2014
4	3,4-dihydroxyphenyllactic acidIBA 01/2018 - 06/2015
3	Adenosine Triphosphate (ATP)IBA 03/2024 - 01/2020
3	chrysinIBA 08/2023 - 07/2015
3	MelatoninIBA 06/2023 - 09/2020
3	LipopolysaccharidesIBA 12/2022 - 01/2019
3	FlavonoidsIBA 12/2021 - 08/2012
3	ProteomeIBA 01/2021 - 02/2015
3	Glutamic Acid (Glutamate)FDA Link 07/2020 - 01/2018
3	CalciumIBA 07/2020 - 01/2014
3	CopperIBA 01/2019 - 04/2018
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2017 - 01/2014
3	indirubinIBA 05/2017 - 12/2015
2	Galactose (Galactopyranose)FDA LinkGeneric 03/2024 - 04/2023
2	InflammasomesIBA 08/2023 - 12/2022
2	Biomarkers (Surrogate Marker)IBA 06/2023 - 01/2018
2	Amyloid beta-PeptidesIBA 01/2023 - 01/2019
2	xanthohumolIBA 12/2021 - 01/2018
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 10/2019
2	AlkaloidsIBA 01/2020 - 01/2018
2	dauricineIBA 01/2020 - 01/2018
2	1,2,3,4-tetrahydroisoquinolineIBA 01/2020 - 01/2018
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020 - 11/2018
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2019 - 10/2016
2	Glycogen Synthase (Synthase I)IBA 01/2019 - 01/2017
2	Donepezil (Aricept)FDA LinkGeneric 01/2019 - 01/2016
2	3- (4- dimethylaminobenzylidene)- 1,3- dihydroindol- 2- oneIBA 11/2017 - 03/2013
2	Monoamine Oxidase (MAO)IBA 11/2017 - 04/2017
2	DT-010IBA 09/2017 - 12/2016
2	Peptides (Polypeptides)IBA 10/2015 - 02/2015
1	Matrix Metalloproteinases (MMPs)IBA 03/2024
1	Hematoxylin (Haematoxylon)IBA 03/2024
1	Eosine Yellowish-(YS) (Eosin)IBA 03/2024
1	NitrogenIBA 11/2023
1	LipidsIBA 08/2023
1	C-Reactive ProteinIBA 06/2023
1	CytokinesIBA 04/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2022
1	Conditioned Culture MediaIBA 04/2022
1	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 02/2022
1	Presenilin-1IBA 02/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2022

Therapy/Procedure

10	Therapeutics 01/2019 - 10/2008
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 01/2021